African Swine Fever: pathogenicity African Swine Fever: pathogenicity The pathogenicity of two groups of African swine fever virus isolates from Cameroon in domestic Pigs

In a previous study on the restriction enzyme analysis of genomes of ASFV isolates from Cameroon (8) it was shown that there are probably two genetically very closely related virus groups persisting within the pig population in the country; one group consists of the CAM/82, CAM/85 CAM/87 and CAM/88 ASFV isolates while the other includes the CAM/86 isolate only. The main differences between the two groups were variations in the size of one fragment occurring in the central region of the genome and two fragments in the right terminal region of the genome (8). One of these isolates, CAM/82, has been previously used to infect pigs and the disease it produced was compared with that produced by other ASFV isolates from Malta, Dominican Republic and Brazil (9). It produced moderate lesions in infected pigs with illdefined clinical signs. The mortality rate was low (33%) and there was clinical recovery of 7 of the infected pigs.